Cargando…
Glutamate induces synthesis of thrombogenic peptides and extracellular vesicle release from human platelets
Platelets are highly sensitive blood cells, which play central role in hemostasis and thrombosis. Platelet dense granules carry considerable amount of neurotransmitter glutamate that is exocytosed upon cell activation. As platelets also express glutamate receptors on their surface, it is pertinent t...
Autores principales: | Gautam, Deepa, Tiwari, Arundhati, Nath Chaurasia, Rameshwar, Dash, Debabrata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554302/ https://www.ncbi.nlm.nih.gov/pubmed/31171802 http://dx.doi.org/10.1038/s41598-019-44734-x |
Ejemplares similares
-
Platelet HIF-2α promotes thrombogenicity through PAI-1 synthesis and extracellular vesicle release
por: Chaurasia, Susheel N., et al.
Publicado: (2019) -
Noncanonical Sonic Hedgehog signaling amplifies platelet reactivity and thrombogenicity
por: Tiwari, Arundhati, et al.
Publicado: (2022) -
Glutamate Receptor Dysregulation and Platelet Glutamate Dynamics in Alzheimer’s and Parkinson’s Diseases: Insights into Current Medications
por: Gautam, Deepa, et al.
Publicado: (2023) -
Fibrinogen Mitigates Prion-Mediated Platelet Activation and Neuronal Cell Toxicity
por: Gautam, Deepa, et al.
Publicado: (2022) -
Notch signaling functions in noncanonical juxtacrine manner in platelets to amplify thrombogenicity
por: Chaurasia, Susheel N, et al.
Publicado: (2022)