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Survival of the simplest in microbial evolution
The evolution of microbial and viral organisms often generates clonal interference, a mode of competition between genetic clades within a population. Here we show how interference impacts systems biology by constraining genetic and phenotypic complexity. Our analysis uses biophysically grounded evol...
Autores principales: | Held, Torsten, Klemmer, Daniel, Lässig, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554311/ https://www.ncbi.nlm.nih.gov/pubmed/31171781 http://dx.doi.org/10.1038/s41467-019-10413-8 |
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