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SUMOylating Two Distinct Sites on the A-type Potassium Channel, Kv4.2, Increases Surface Expression and Decreases Current Amplitude

Post-translational conjugation of Small Ubiquitin-like Modifier (SUMO) peptides to lysine (K) residues on target proteins alters their interactions. SUMOylation of a target protein can either promote its interaction with other proteins that possess SUMO binding domains, or it can prevent target prot...

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Detalles Bibliográficos
Autores principales: Welch, Meghyn A., Forster, Lori A., Atlas, Selin I., Baro, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554448/
https://www.ncbi.nlm.nih.gov/pubmed/31213982
http://dx.doi.org/10.3389/fnmol.2019.00144