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Selective Neural Deletion of the Atg7 Gene Reduces Irradiation-Induced Cerebellar White Matter Injury in the Juvenile Mouse Brain by Ameliorating Oligodendrocyte Progenitor Cell Loss
Radiotherapy is an effective tool for treating brain tumors, but irradiation-induced toxicity to the normal brain tissue remains a major problem. Here, we investigated if selective neural autophagy related gene 7 (Atg7) deletion has a persistent effect on irradiation-induced juvenile mouse brain inj...
Autores principales: | Wang, Yafeng, Zhou, Kai, Li, Tao, Xu, Yiran, Xie, Cuicui, Sun, Yanyan, Rodriguez, Juan, Zhang, Shan, Song, Juan, Wang, Xiaoyang, Blomgren, Klas, Zhu, Changlian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554477/ https://www.ncbi.nlm.nih.gov/pubmed/31213984 http://dx.doi.org/10.3389/fncel.2019.00241 |
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