miR-577 Regulates TGF-β Induced Cancer Progression through a SDPR-Modulated Positive-Feedback Loop with ERK-NF-κB in Gastric Cancer

Transforming growth factor β (TGF-β) drives epithelial-mesenchymal transition (EMT), playing vital roles in cancer metastasis. The crosstalk between microRNAs (miRNAs) and TGF-β are frequently observed and involved in TGF-β-induced EMT. Here, we determine that miR-577 is significantly upregulated in...

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Detalles Bibliográficos
Autores principales: Luo, Yuhao, Wu, Jianhua, Wu, Qianying, Li, Xiaoyin, Wu, Jiani, Zhang, Jingwen, Rong, Xiaoxiang, Rao, Jingjun, Liao, Yulin, Bin, Jianping, Huang, Na, Liao, Wangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554531/
https://www.ncbi.nlm.nih.gov/pubmed/30879950
http://dx.doi.org/10.1016/j.ymthe.2019.02.002

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