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Human Toll-like Receptor 8 (TLR8) Is an Important Sensor of Pyogenic Bacteria, and Is Attenuated by Cell Surface TLR Signaling

TLR8 is an endosomal sensor of RNA degradation products in human phagocytes, and is involved in the recognition of viral and bacterial pathogens. We previously showed that in human primary monocytes and monocyte derived macrophages, TLR8 senses entire Staphylococcus aureus and Streptococcus agalacti...

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Detalles Bibliográficos
Autores principales:	Moen, Siv H., Ehrnström, Birgitta, Kojen, June F., Yurchenko, Mariia, Beckwith, Kai S., Afset, Jan E., Damås, Jan K., Hu, Zhenyi, Yin, Hang, Espevik, Terje, Stenvik, Jørgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554558/ https://www.ncbi.nlm.nih.gov/pubmed/31214180 http://dx.doi.org/10.3389/fimmu.2019.01209

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