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Potentiating Oncolytic Virus-Induced Immune-Mediated Tumor Cell Killing Using Histone Deacetylase Inhibition

A clinical oncolytic herpes simplex virus (HSV) encoding granulocyte-macrophage colony-stimulating factor (GM-CSF), talimogene laherparepvec, causes regression of injected and non-injected melanoma lesions in patients and is now licensed for clinical use in advanced melanoma. To date, limited data a...

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Detalles Bibliográficos
Autores principales:	Jennings, Victoria A., Scott, Gina B., Rose, Ailsa M.S., Scott, Karen J., Migneco, Gemma, Keller, Brian, Reilly, Katrina, Donnelly, Oliver, Peach, Howard, Dewar, Donald, Harrington, Kevin J., Pandha, Hardev, Samson, Adel, Vile, Richard G., Melcher, Alan A., Errington-Mais, Fiona
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554638/ https://www.ncbi.nlm.nih.gov/pubmed/31053413 http://dx.doi.org/10.1016/j.ymthe.2019.04.008

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