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OR30-5 Germline Ablation of G-Protein Subunit Alpha-11 in Mice Causes Hypercalcemia That Is Rectified by Treatment with Cinacalcet
G-protein subunit α-(11) (Gα(11)) is a signalling partner of the calcium-sensing receptor (CaSR), which is a G-protein coupled receptor that plays a major role in calcium homeostasis by regulating parathyroid hormone (PTH) secretion, urinary calcium excretion and skeletal development. Although loss-...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554764/ http://dx.doi.org/10.1210/js.2019-OR30-5 |