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OR29-3 Targeted Assessment of G0S2 Methylation Identifies a Rapidly Recurrent, Routinely Fatal Molecular Subtype of Adrenocortical Carcinoma
Adrenocortical carcinoma (ACC) is a rare malignancy with frequently dismal prognosis and few therapies. Patients with locoregional ACC routinely receive surgery and adjuvant mitotane, but >50% recur with metastases even after complete resection. Histological grade (Ki67>10% or >20 mitoses/5...
Autores principales: | Mohan, Dipika, Lerario, Antonio, Else, Tobias, Almeida, Madson, Vinco, Michelle, Rege, Juilee, Mariani, Beatriz, Zerbini, Maria, Mendonca, Berenice, Latronico, Ana Claudia, Marie, Suely, Rainey, William, Giordano, Thomas, Fragoso, Maria, Hammer, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554777/ http://dx.doi.org/10.1210/js.2019-OR29-3 |
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