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OR02-5 Novel Intermediates Are Catalysed By 11βHSD And CYP17A1 In The C11-oxy Backdoor Pathway Leading To The Production Of 11-ketodihydrotestosterone
Adrenal C(19) steroids, testosterone and androstenedione, have long been the only androgens considered contributing to clinical conditions characterised by androgen excess. More recently, we showed that adrenal 11β-hydroxyandrostenedione is converted to 11-ketotestosterone and 11-ketodihydrotestoste...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Endocrine Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554786/ http://dx.doi.org/10.1210/js.2019-OR02-5 |