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OR08-3 The Role Of Neuronal Plasticity In The Timing Of Puberty Onset: Insights From A Mkrn3 Deficient Mouse Model.
Makorin ring finger protein 3 (MKRN3) was identified as a regulator of puberty initiation with the report of loss-of-function mutations in association with central precocious puberty (CPP). MKRN3 is a maternally imprinted gene located on chromosome 15q11.2 in humans. In juvenile mice, Mkrn3 is highl...
Autores principales: | Naule, Lydie, Abreu, Ana Paula, Gassaway, Brandon, Kim, Han Kyeol, Liang, Joy, Carroll, Rona, Gygi, Steven, Kaiser, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554802/ http://dx.doi.org/10.1210/js.2019-OR08-3 |
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