Cargando…
OR26-4 Genome-Wide Binding Profile of Phosphorylated Estrogen Receptor Reveals Association with Direct DNA Binding
Post-translational modifications are key regulators of protein function, providing signals that alter protein interactions and activity. Phosphorylation of estrogen receptor-α (ER) at serine 118 (pS118-ER) occurs in response to multiple stimuli and is involved in modulating ER-dependent gene transcr...
Autores principales: | Helzer, Kyle, Szatkowski Ozers, Mary, Meyer, Mark, Benkusky, Nancy, Solodin, Natalia, Reese, Rebecca, Warren, Christopher, Pike, J, Alarid, Elaine |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554808/ http://dx.doi.org/10.1210/js.2019-OR26-4 |
Ejemplares similares
-
The Transcriptional Function of GRHL2 in Hormone-Dependent Breast Cancers
por: Reese, Rebecca, et al.
Publicado: (2021) -
SUN-012 Investigating the Effect of GRHL2 on pS118-ER Transcriptional Activity in Breast Cancer
por: Reese, Rebecca, et al.
Publicado: (2019) -
OR26-2 Phosphorylation of Estrogen Receptor Alpha is Required for Mammary Gland Development and MCF-7 Breast Tumor Response to Estradiol and Tamoxifen
por: Emneser, Waleed, et al.
Publicado: (2019) -
OR26-5 Functional Analysis of Estrogen-Regulated Enhancer RNAs in Breast Cancer Cells
por: Hou, Tim, et al.
Publicado: (2019) -
OR26-3 ERK1/2-RSK2 Maintains Estrogen Homeostasis in the Adult Mammary Gland
por: Sandusky, Zachary
Publicado: (2019)