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OR26-3 ERK1/2-RSK2 Maintains Estrogen Homeostasis in the Adult Mammary Gland
In response to estrogens, estrogen receptor alpha (ERα) is degraded by the 26S proteasome; however, despite the continued presence of estrogen prior to menopause, ERα protein levels are maintained by an unidentified mechanism. We find that the Ser/Thr kinase, RSK2, negatively regulates ERK1/2-depend...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Endocrine Society
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554916/ http://dx.doi.org/10.1210/js.2019-OR26-3 |