OR07-2 Elucidating The Mechanisms Of Action Of Mkrn3 In A Novel Mouse Model Of Delayed Puberty.

Makorin Ring Finger Protein 3 (MKRN3) is an important neuroendocrine player in the control of pubertal timing. Loss-of-function mutations in MKRN3 are the most common genetic cause of central precocious puberty. Mice have high levels of hypothalamic Mkrn3 expression in the juvenile period, which rap...

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Detalles Bibliográficos
Autores principales: Roberts, Stephanie, Chouman, Soukayna, Johnson, Marciana, Navarro, Victor, Carroll, Rona, Kaiser, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Pediatric Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554928/
http://dx.doi.org/10.1210/js.2019-OR07-2

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