Tumor-secreted PAI-1 promotes breast cancer metastasis via the induction of adipocyte-derived collagen remodeling

BACKGROUND: Breast cancer cells recruit surrounding stromal cells, such as cancer-associated fibroblasts (CAFs), to remodel collagen and promote tumor metastasis. Adipocytes are the most abundant stromal partners in breast tissue, local invasion of breast cancer leads to the proximity of cancer cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Wei, Xiaohui, Li, Sijing, He, Jinyong, Du, Hongzhi, Liu, Yang, Yu, Wei, Hu, Haolin, Han, Lifei, Wang, Chenfei, Li, Hongyang, Shi, Xin, Zhan, Meixiao, Lu, Ligong, Yuan, Shengtao, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6554964/
https://www.ncbi.nlm.nih.gov/pubmed/31170987
http://dx.doi.org/10.1186/s12964-019-0373-z

Ejemplares similares

Ejemplares similares