OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?

Background: Septic patients often develop muscle weakness, contributing to ICU morbidity and mortality. We recently observed that obese septic mice and patients do not develop such weakness, explained by increased lipolysis and hepatic conversion of fatty acids into the ketone bodies. Furthermore, i...

Descripción completa

Detalles Bibliográficos
Autores principales: Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Vander Perre, Sarah, Pauwels, Lies, Van den Berghe, Greet, Langouche, Lies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Adipose Tissue, Appetite, and Obesity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555032/
http://dx.doi.org/10.1210/js.2019-OR20-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555032/
http://dx.doi.org/10.1210/js.2019-OR20-6

Ejemplares similares