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OR20-6 Ketones and Sepsis-Induced Muscle Weakness: Signal or Fuel for Protection?
Background: Septic patients often develop muscle weakness, contributing to ICU morbidity and mortality. We recently observed that obese septic mice and patients do not develop such weakness, explained by increased lipolysis and hepatic conversion of fatty acids into the ketone bodies. Furthermore, i...
Autores principales: | Weckx, Ruben, Goossens, Chloë, Derde, Sarah, Vander Perre, Sarah, Pauwels, Lies, Van den Berghe, Greet, Langouche, Lies |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555032/ http://dx.doi.org/10.1210/js.2019-OR20-6 |
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