Cargando…

OR15-5 Human Sex Determination at the Edge of Ambiguity: Impaired SRY Phosphorylation Attenuates Expression of the Male Program

A paradox is posed by metazoan gene-regulatory networks (GRNs) that are robust yet evolvable. Insight may be obtained through studies of bistable genetic circuits mediating developmental decisions. A model in organogenesis is provided by the sex-specific differentiation of the embryonic gonadal ridg...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yen-Shan, Racca, Joseph, Phillips, Nelson, Weiss, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555045/
http://dx.doi.org/10.1210/js.2019-OR15-5

Ejemplares similares