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OR01-3 MicroRNA-34a-Mediated FGF21 Resistance in the Adipose Tissue Contributes to Insulin Resistance and Hypoadiponectinemia in Diet-Induced Obesity

Background and Objective: Fibroblast growth factor 21 (FGF21) is a metabolic hormone with multiple beneficial effects on glucose and lipid homeostasis, in part mediated through its stimulatory effect on adiponectin secretion. However, FGF21 circulating levels are paradoxically elevated in obesity, t...

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Detalles Bibliográficos
Autores principales:	Pan, Yong, Feng, Tianshi, Chan, Yuk-Cheung, Xu, Aimin, Lam, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Adipose Tissue, Appetite, and Obesity
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555059/ http://dx.doi.org/10.1210/js.2019-OR01-3

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