Cargando…

OR04-3 Lysine-Specific Demethylase-1 (LSD1) Deficiency Increases Aldosterone Signaling via Mineralocorticoid Receptor Activation

Lysine-specific demethylase-1 (LSD1) is a histone demethylase that mediates epigenetic regulation of gene transcription. We have shown that human risk allele carriers of a LSD1 variant as well as a LSD1 heterozygous knockout mice (LSD1(+/-)) have salt sensitive hypertension (HTN), but low aldosteron...

Descripción completa

Detalles Bibliográficos
Autores principales:	Treesaranuwattana, Thitinan, Williams, Gordon, Pojoga, Luminita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Endocrine Society 2019
Materias:	Cardiovascular Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555081/ http://dx.doi.org/10.1210/js.2019-OR04-3

Ejemplares similares

SUN-LB91 The Arg16/Gln27 Polymorphism of the Beta2-Adrenergic Receptor Impacts Blood Pressure Levels in a Transgenic Mouse Model via Sex-Specific Mechanisms
por: Treesaranuwattana, Thitinan, et al.
Publicado: (2020)

FRI153 Genetic Variant In Armadillo Repeat Containing 5 Gene (ARMC5) Associates With Salt Sensitivity Of Blood Pressure And Aldosterone In A Caucasian Cohort
por: Parksook, Wasita W, et al.
Publicado: (2023)

SAT-564 Effectiveness of Treatment with Mineralocorticoid Receptor Antagonistsin Primary Aldosteronism
por: Tezuka, Yuta, et al.
Publicado: (2020)

SAT-561 Effects of Mineralocorticoid Receptor Antagonists on Primary Aldosteronism Screening
por: Tezuka, Yuta, et al.
Publicado: (2020)

PSUN68 Finerenone for Primary Aldosteronism: A Novel Mineralocorticoid Receptor Antagonist
por: Aurora, John, et al.
Publicado: (2022)

SAT-051 Higher Urinary Cortisol Levels Associated with Increased Cardiovascular Risk
por: Haas, Andrea, et al.
Publicado: (2019)

Roles of lysine-specific demethylase 1 (LSD1) in homeostasis and diseases
por: Kim, Dongha, et al.
Publicado: (2021)

OR04-1 Dietary Sodium Intake, the Renin-Angiotensin-Aldosterone System, and the Risk for Incident Kidney Stones
por: Bayomy, Omar, et al.
Publicado: (2019)

OR02-04 Peripheral Blood Steroid Profiling Discriminates Aldosterone-producing Adenoma Genotypes From Bilateral Primary Aldosteronism
por: Turcu, Adina F, et al.
Publicado: (2023)

Expanding the Role of the Histone Lysine-Specific Demethylase LSD1 in Cancer
por: Majello, Barbara, et al.
Publicado: (2019)

Role of Aldosterone and Mineralocorticoid Receptor in Cardiovascular Aging
por: Gorini, Stefania, et al.
Publicado: (2019)

OR04-6 Predictors of Clinical Outcome after Adrenalectomy for Unilateral Primary Aldosteronism
por: Moises, Caio, et al.
Publicado: (2019)

OR04-2 Aldosterone Induces Trained Immunity via Fatty Acid Synthesis
por: van der Heijden, Charlotte, et al.
Publicado: (2019)

Lysine-specific histone demethylase 1A (LSD1) in cervical cancer
por: Beilner, Daniel, et al.
Publicado: (2020)

Lysine-Specific Demethylase 1 (LSD1) epigenetically controls osteoblast differentiation
por: Rummukainen, Petri, et al.
Publicado: (2022)

Striatin heterozygous mice are more sensitive to aldosterone-induced injury
por: Garza, Amanda E, et al.
Publicado: (2020)

FRI141 Dietary Salt Regulates mTORC1 Signaling In Humans And Mice With Hypertension
por: Aljaibeji, Hayat, et al.
Publicado: (2023)

The Catalytic-Dependent and -Independent Roles of Lsd1 and Lsd2 Lysine Demethylases in Heterochromatin Formation in Schizosaccharomyces pombe
por: Marayati, Bahjat F., et al.
Publicado: (2020)

OR34-04 Efficiency of Adrenal Venous Sampling in the Treatment Choice of Primary Aldosteronism (AVSTAT Study)
por: Naruse, Mitsuhide, et al.
Publicado: (2020)

Novel spirocyclic tranylcypromine derivatives as lysine-specific demethylase 1 (LSD1) inhibitors
por: Shi, Ying, et al.
Publicado: (2018)

Real-World Effectiveness of Mineralocorticoid Receptor Antagonists in Primary Aldosteronism
por: Tezuka, Yuta, et al.
Publicado: (2021)

Catalytic Mechanism Investigation of Lysine-Specific Demethylase 1 (LSD1): A Computational Study
por: Kong, Xiangqian, et al.
Publicado: (2011)

SAT-550 Changes in Albuminuria Precede Dietary Sodium-Dependent Changes in BP During Aging - a Longitudinal Study
por: Katayama, Isis Akemi, et al.
Publicado: (2020)

Lysine-specific demethylase 1 (LSD1) destabilizes p62 and inhibits autophagy in gynecologic malignancies
por: Chao, Angel, et al.
Publicado: (2017)

Lysine-Specific Demethylase 1 (LSD1)-Mediated Epigenetic Modification of Immunogenicity and Immunomodulatory Effects in Breast Cancers
por: Lee, Dong Yeul, et al.
Publicado: (2023)

The Epigenetic Controller Lysine-Specific Demethylase 1 (LSD1) Regulates the Outcome of Hepatitis C Viral Infection
por: Papadopoulou, Georgia, et al.
Publicado: (2023)

Lysine-specific demethylase LSD1 regulates autophagy in neuroblastoma through SESN2-dependent pathway
por: Ambrosio, S, et al.
Publicado: (2017)

Lysine-Specific Demethylase 1 (LSD1/KDM1A) Inhibition as a Target for Disease Modification in Myelofibrosis
por: Gill, Harinder
Publicado: (2022)

Lysine-Specific Demethylase 1 (LSD1) Is Required for the Transcriptional Repression of the Telomerase Reverse Transcriptase (hTERT) Gene
por: Zhu, Qingjun, et al.
Publicado: (2008)

Lysine-specific demethylase (LSD1/KDM1A) and MYCN cooperatively repress tumor suppressor genes in neuroblastoma
por: Amente, Stefano, et al.
Publicado: (2015)

Functional characterization of lysine-specific demethylase 2 (LSD2/KDM1B) in breast cancer progression
por: Chen, Lin, et al.
Publicado: (2017)

FRI132 Aldosterone Secretory Capacity Immediately After Surgery Predicts Biochemical Outcome 1 Year After Surgery In Primary Aldosteronism
por: Ishida, Yuto, et al.
Publicado: (2023)

SAT-543 Human Hair Aldosterone Measurements for Evaluation of Primary Aldosteronism
por: Demidowich, Andrew Paul, et al.
Publicado: (2020)

SAT-547 Aldosterone-Potassium Ratio Predicts Primary Aldosteronism Subtype
por: Puar, Troy, et al.
Publicado: (2020)

Analysis of the levels of lysine-specific demethylase 1 (LSD1) mRNA in human ovarian tumors and the effects of chemical LSD1 inhibitors in ovarian cancer cell lines
por: Konovalov, Sergiy, et al.
Publicado: (2013)

OR02-01 Somatic Mutations In The Zinc Transporter ZnT1 Cause Primary Aldosteronism
por: Rege, Juilee, et al.
Publicado: (2023)

SAT-544 Primary Aldosteronism in Intracerebral Hemorrhage. Not Intracerebral Hemorrhage in Primary Aldosteronism
por: Arai, Makoto, et al.
Publicado: (2020)

Laterality Diagnosis of Adrenal Vein Sampling for Primary Aldosteronism Using Aldosterone Alone
por: Wada, Norio, et al.
Publicado: (2021)

OR02-03 Twenty-four-hour Tissue Microdialysis Of Aldosterone And Metabolites In Primary Aldosteronism
por: Aardal Grytaas, Marianne, et al.
Publicado: (2023)

SAT-059 Treatment Of Primary Aldosteronism With The mTORC1 Inhibitor Everolimus
por: Trinh, Beckey, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1lum3r96001be8v3hhjadbo3cb