Enzymatic Activities of CYP3A4 Allelic Variants on Quinine 3-Hydroxylation In Vitro

Cytochrome P450 3A4 (CYP3A4) enzyme activity is known to show considerable ethnic heterogeneity and inter-individual differences, affecting the outcome of drug treatment. CYP3A4 genetic polymorphisms are believed to be one of the important causes, leading to inter-individual variability in drug meta...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao-Yang, Hu, Xiao-Xia, Wang, Chen-Chen, Lu, Xiang-Ran, Chen, Zhe, Liu, Qian, Hu, Guo-Xin, Cai, Jian-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555127/
https://www.ncbi.nlm.nih.gov/pubmed/31214030
http://dx.doi.org/10.3389/fphar.2019.00591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555127/
https://www.ncbi.nlm.nih.gov/pubmed/31214030
http://dx.doi.org/10.3389/fphar.2019.00591

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