ABioTrans: A Biostatistical Tool for Transcriptomics Analysis

Here we report a bio-statistical/informatics tool, ABioTrans, developed in R for gene expression analysis. The tool allows the user to directly read RNA-Seq data files deposited in the Gene Expression Omnibus or GEO database. Operated using any web browser application, ABioTrans provides easy option...

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Detalles Bibliográficos
Autores principales: Zou, Yutong, Bui, Thuy Tien, Selvarajoo, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555198/
https://www.ncbi.nlm.nih.gov/pubmed/31214245
http://dx.doi.org/10.3389/fgene.2019.00499
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author Zou, Yutong
Bui, Thuy Tien
Selvarajoo, Kumar
author_facet Zou, Yutong
Bui, Thuy Tien
Selvarajoo, Kumar
author_sort Zou, Yutong
collection PubMed
description Here we report a bio-statistical/informatics tool, ABioTrans, developed in R for gene expression analysis. The tool allows the user to directly read RNA-Seq data files deposited in the Gene Expression Omnibus or GEO database. Operated using any web browser application, ABioTrans provides easy options for multiple statistical distribution fitting, Pearson and Spearman rank correlations, PCA, k-means and hierarchical clustering, differential expression (DE) analysis, Shannon entropy and noise (square of coefficient of variation) analyses, as well as Gene ontology classifications.
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spelling pubmed-65551982019-06-18 ABioTrans: A Biostatistical Tool for Transcriptomics Analysis Zou, Yutong Bui, Thuy Tien Selvarajoo, Kumar Front Genet Genetics Here we report a bio-statistical/informatics tool, ABioTrans, developed in R for gene expression analysis. The tool allows the user to directly read RNA-Seq data files deposited in the Gene Expression Omnibus or GEO database. Operated using any web browser application, ABioTrans provides easy options for multiple statistical distribution fitting, Pearson and Spearman rank correlations, PCA, k-means and hierarchical clustering, differential expression (DE) analysis, Shannon entropy and noise (square of coefficient of variation) analyses, as well as Gene ontology classifications. Frontiers Media S.A. 2019-05-31 /pmc/articles/PMC6555198/ /pubmed/31214245 http://dx.doi.org/10.3389/fgene.2019.00499 Text en Copyright © 2019 Zou, Bui and Selvarajoo. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Zou, Yutong
Bui, Thuy Tien
Selvarajoo, Kumar
ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title_full ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title_fullStr ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title_full_unstemmed ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title_short ABioTrans: A Biostatistical Tool for Transcriptomics Analysis
title_sort abiotrans: a biostatistical tool for transcriptomics analysis
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555198/
https://www.ncbi.nlm.nih.gov/pubmed/31214245
http://dx.doi.org/10.3389/fgene.2019.00499
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AT buithuytien abiotransabiostatisticaltoolfortranscriptomicsanalysis
AT selvarajookumar abiotransabiostatisticaltoolfortranscriptomicsanalysis

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