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The Multi-faceted Ecto-enzyme CD38: Roles in Immunomodulation, Cancer, Aging, and Metabolic Diseases

CD38 (Cluster of Differentiation 38) is a multifunctional ecto-enzyme that metabolizes NAD+ and mediates nicotinamide dinucleotide (NAD+) and extracellular nucleotide homeostasis as well as intracellular calcium. CD38 is also an emerging therapeutic target under conditions in which metabolism is alt...

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Detalles Bibliográficos
Autores principales: Hogan, Kelly A., Chini, Claudia C. S., Chini, Eduardo N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555258/
https://www.ncbi.nlm.nih.gov/pubmed/31214171
http://dx.doi.org/10.3389/fimmu.2019.01187