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Surgical Excision of an Adrenal Neuroblastoma in a Dog

A 11-month-old, intact male, Rhodesian Ridgeback was presented to the Veterinary Teaching Hospital with signs of inappetence, lethargy, and abdominal pain for 3 days. A large and well-defined abdominal retroperitoneal mass, related with the left kidney, at the expected location of the adrenal gland,...

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Autores principales: Mestrinho, Lisa Alexandra, Marques, Maria Inês, Jesus, Sandra, Pissarra, Hugo, Peleteiro, Maria, Ferreira, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555272/
https://www.ncbi.nlm.nih.gov/pubmed/31214604
http://dx.doi.org/10.3389/fvets.2019.00161
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author Mestrinho, Lisa Alexandra
Marques, Maria Inês
Jesus, Sandra
Pissarra, Hugo
Peleteiro, Maria
Ferreira, Antonio
author_facet Mestrinho, Lisa Alexandra
Marques, Maria Inês
Jesus, Sandra
Pissarra, Hugo
Peleteiro, Maria
Ferreira, Antonio
author_sort Mestrinho, Lisa Alexandra
collection PubMed
description A 11-month-old, intact male, Rhodesian Ridgeback was presented to the Veterinary Teaching Hospital with signs of inappetence, lethargy, and abdominal pain for 3 days. A large and well-defined abdominal retroperitoneal mass, related with the left kidney, at the expected location of the adrenal gland, was revealed by radiography, ultrasound, and computed tomography. The mass extended caudally to the iliac artery bifurcation, compressing the aorta, caudal vena cava, and both kidneys. Cytology findings were compatible with a malignant round cell tumor. The most probable diagnosis was neuroblastoma. Following a comprehensive discussion with the owners about a treatment plan, surgical excision was performed. Because a wide excision would compromise major vessels, excision was performed after careful dissection of the aorta and vena cava. The left kidney was removed because the proximal ureter could not be separated from the tumor. The animal recovered successfully. Diagnosis was confirmed by histopathology and immunohistochemistry, but the owners decided not to pursue any further treatment. Clinical signs of abdominal pain recurred within 1 month following surgery. Therefore, the animal was euthanized upon the owners' request. This report describes the diagnosis, surgical treatment, and follow-up of a dog with an abdominal peripheral neuroblastoma.
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spelling pubmed-65552722019-06-18 Surgical Excision of an Adrenal Neuroblastoma in a Dog Mestrinho, Lisa Alexandra Marques, Maria Inês Jesus, Sandra Pissarra, Hugo Peleteiro, Maria Ferreira, Antonio Front Vet Sci Veterinary Science A 11-month-old, intact male, Rhodesian Ridgeback was presented to the Veterinary Teaching Hospital with signs of inappetence, lethargy, and abdominal pain for 3 days. A large and well-defined abdominal retroperitoneal mass, related with the left kidney, at the expected location of the adrenal gland, was revealed by radiography, ultrasound, and computed tomography. The mass extended caudally to the iliac artery bifurcation, compressing the aorta, caudal vena cava, and both kidneys. Cytology findings were compatible with a malignant round cell tumor. The most probable diagnosis was neuroblastoma. Following a comprehensive discussion with the owners about a treatment plan, surgical excision was performed. Because a wide excision would compromise major vessels, excision was performed after careful dissection of the aorta and vena cava. The left kidney was removed because the proximal ureter could not be separated from the tumor. The animal recovered successfully. Diagnosis was confirmed by histopathology and immunohistochemistry, but the owners decided not to pursue any further treatment. Clinical signs of abdominal pain recurred within 1 month following surgery. Therefore, the animal was euthanized upon the owners' request. This report describes the diagnosis, surgical treatment, and follow-up of a dog with an abdominal peripheral neuroblastoma. Frontiers Media S.A. 2019-05-29 /pmc/articles/PMC6555272/ /pubmed/31214604 http://dx.doi.org/10.3389/fvets.2019.00161 Text en Copyright © 2019 Mestrinho, Marques, Jesus, Pissarra, Peleteiro and Ferreira. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Mestrinho, Lisa Alexandra
Marques, Maria Inês
Jesus, Sandra
Pissarra, Hugo
Peleteiro, Maria
Ferreira, Antonio
Surgical Excision of an Adrenal Neuroblastoma in a Dog
title Surgical Excision of an Adrenal Neuroblastoma in a Dog
title_full Surgical Excision of an Adrenal Neuroblastoma in a Dog
title_fullStr Surgical Excision of an Adrenal Neuroblastoma in a Dog
title_full_unstemmed Surgical Excision of an Adrenal Neuroblastoma in a Dog
title_short Surgical Excision of an Adrenal Neuroblastoma in a Dog
title_sort surgical excision of an adrenal neuroblastoma in a dog
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555272/
https://www.ncbi.nlm.nih.gov/pubmed/31214604
http://dx.doi.org/10.3389/fvets.2019.00161
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