A new heparan sulfate from the mollusk Nodipecten nodosus inhibits merozoite invasion and disrupts rosetting and cytoadherence of Plasmodium falciparum

BACKGROUND: Despite treatment with effective antimalarial drugs, the mortality rate is still high in severe cases of the disease, highlighting the need to find adjunct therapies that can inhibit the adhesion of Plasmodium falciparum-infected erythrocytes (Pf-iEs). OBJECTIVES: In this context, we eva...

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Detalles Bibliográficos
Autores principales: Bastos, Marcele F, Albrecht, Letusa, Gomes, Angélica M, Lopes, Stefanie CP, Vicente, Cristina P, de Almeida, Rodrigo PM, Cassiano, Gustavo C, Fonseca, Roberto JC, Werneck, Claudio C, Pavão, Mauro SG, Costa, Fabio TM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555591/
https://www.ncbi.nlm.nih.gov/pubmed/31188952
http://dx.doi.org/10.1590/0074-02760190088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555591/
https://www.ncbi.nlm.nih.gov/pubmed/31188952
http://dx.doi.org/10.1590/0074-02760190088

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