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Tolerability of BRAF/MEK inhibitor combinations: adverse event evaluation and management

The inhibition of the mitogen-activated protein kinases signalling pathway through combined use of BRAF and MEK inhibitors (BRAFi+MEKi) represents an established therapeutic option in patients with BRAF-mutated, advanced melanoma. These efficient therapies are well tolerated with mostly moderate and...

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Detalles Bibliográficos
Autores principales:	Heinzerling, Lucie, Eigentler, Thomas K, Fluck, Michael, Hassel, Jessica C, Heller-Schenck, Daniela, Leipe, Jan, Pauschinger, Matthias, Vogel, Arndt, Zimmer, Lisa, Gutzmer, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555610/ https://www.ncbi.nlm.nih.gov/pubmed/31231568 http://dx.doi.org/10.1136/esmoopen-2019-000491

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