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Culturing C2C12 myotubes on micromolded gelatin hydrogels accelerates myotube maturation

BACKGROUND: Skeletal muscle contributes to roughly 40% of lean body mass, and its loss contributes to morbidity and mortality in a variety of pathogenic conditions. Significant insights into muscle function have been made using cultured cells, in particular, the C2C12 myoblast line. However, differe...

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Detalles Bibliográficos
Autores principales: Denes, Lance T., Riley, Lance A., Mijares, Joseph R., Arboleda, Juan D., McKee, Kendra, Esser, Karyn A., Wang, Eric T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555731/
https://www.ncbi.nlm.nih.gov/pubmed/31174599
http://dx.doi.org/10.1186/s13395-019-0203-4

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