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A novel lncRNA-miRNA-mRNA triple network identifies lncRNA TWF1 as an important regulator of miRNA and gene expression in coronary artery disease

BACKGROUND: Long non-coding RNAs (lncRNAs) are involved in numerous physiological functions. Yet, their mechanisms in coronary artery disease (CAD) are not well understood. METHODS: The expression profile of genes associated to CAD was reannotated into the lncRNA-mRNA biphasic profile. The target mi...

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Detalles Bibliográficos
Autores principales: Miao, Liu, Yin, Rui-Xing, Zhang, Qing-Hui, Hu, Xi-Jiang, Huang, Feng, Chen, Wu-Xian, Cao, Xiao-Li, Wu, Jin-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555741/
https://www.ncbi.nlm.nih.gov/pubmed/31182968
http://dx.doi.org/10.1186/s12986-019-0366-3