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A novel RNA aptamer identifies plasma membrane ATP synthase beta subunit as an early marker and therapeutic target in aggressive cancer

PURPOSE: Primary breast and prostate cancers can be cured, but metastatic disease cannot. Identifying cell factors that predict metastatic potential could guide both prognosis and treatment. METHODS: We used Cell-SELEX to screen an RNA aptamer library for differential binding to prostate cancer cell...

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Detalles Bibliográficos
Autores principales: Speransky, S., Serafini, P., Caroli, J., Bicciato, S., Lippman, M. E., Bishopric, N. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555781/
https://www.ncbi.nlm.nih.gov/pubmed/31006104
http://dx.doi.org/10.1007/s10549-019-05174-3