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Polygenic risk associated with post-traumatic stress disorder onset and severity

Post-traumatic stress disorder (PTSD) is a psychiatric illness with a highly polygenic architecture without large effect-size common single-nucleotide polymorphisms (SNPs). Thus, to capture a substantial portion of the genetic contribution, effects from many variants need to be aggregated. We invest...

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Detalles Bibliográficos
Autores principales: Misganaw, Burook, Guffanti, Guia, Lori, Adriana, Abu-Amara, Duna, Flory, Janine D., Mueller, Susanne, Yehuda, Rachel, Jett, Marti, Marmar, Charles R., Ressler, Kerry J., Doyle, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555815/
https://www.ncbi.nlm.nih.gov/pubmed/31175274
http://dx.doi.org/10.1038/s41398-019-0497-3