Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity

The type II nuclear receptors (NRs) function as heterodimeric transcription factors with the retinoid X receptor (RXR) to regulate diverse biological processes in response to endogenous ligands and therapeutic drugs. DNA-binding specificity has been proposed as a primary mechanism for NR gene regula...

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Detalles Bibliográficos
Autores principales: Penvose, Ashley, Keenan, Jessica L., Bray, David, Ramlall, Vijendra, Siggers, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555819/
https://www.ncbi.nlm.nih.gov/pubmed/31175293
http://dx.doi.org/10.1038/s41467-019-10264-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555819/
https://www.ncbi.nlm.nih.gov/pubmed/31175293
http://dx.doi.org/10.1038/s41467-019-10264-3

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