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Comprehensive study of nuclear receptor DNA binding provides a revised framework for understanding receptor specificity
The type II nuclear receptors (NRs) function as heterodimeric transcription factors with the retinoid X receptor (RXR) to regulate diverse biological processes in response to endogenous ligands and therapeutic drugs. DNA-binding specificity has been proposed as a primary mechanism for NR gene regula...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555819/ https://www.ncbi.nlm.nih.gov/pubmed/31175293 http://dx.doi.org/10.1038/s41467-019-10264-3 |