Cargando…

Enantioselective synthesis of cis-hydrobenzofurans bearing all-carbon quaternary stereocenters and application to total synthesis of (‒)-morphine

(‒)-Morphine, which is selected as an essential medicine by World Health Organization, is widely applied in the treatment of the pain-related diseases. Due to its synthetically challenging molecular architecture and important clinical role, extensive synthetic studies of morphine-type alkaloids have...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Qing, Zhang, Fu-Min, Zhang, Chang-Sheng, Liu, Si-Zhan, Tian, Jin-Miao, Wang, Shao-Hua, Zhang, Xiao-Ming, Tu, Yong-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555830/ https://www.ncbi.nlm.nih.gov/pubmed/31175289 http://dx.doi.org/10.1038/s41467-019-10398-4

Ejemplares similares

Enantioselective Construction of Remote Quaternary Stereocenters
por: Mei, Tian-Sheng, et al.
Publicado: (2014)

Enantioselective Synthesis of Aza-Flavanones with an All-Carbon Quaternary Stereocenter via NHC-Catalyzed Intramolecular Annulation
por: Barańska, Izabela, et al.
Publicado: (2023)

Enantioselective Synthesis of Acyclic Orthogonally Functionalized Compounds Bearing a Quaternary Stereocenter Using Chiral Ammonium Salt Catalysis
por: Röser, Katharina, et al.
Publicado: (2021)

Enantioselective Narasaka–Heck cyclizations: synthesis of tetrasubstituted nitrogen-bearing stereocenters
por: Race, Nicholas J., et al.
Publicado: (2017)

Catalytic enantioselective construction of vicinal quaternary carbon stereocenters
por: Zhou, Feng, et al.
Publicado: (2020)

Stereodivergent synthesis of vicinal quaternary-quaternary stereocenters and bioactive hyperolactones
por: Zheng, Haifeng, et al.
Publicado: (2018)

Catalytic Enantioselective Entry to Triflones Featuring a Quaternary Stereocenter
por: Franco, Francesca, et al.
Publicado: (2022)

Enantioselective construction of triaryl-substituted all-carbon quaternary stereocenters via organocatalytic arylation of oxindoles with azonaphthalenes
por: Chen, Pengquan, et al.
Publicado: (2023)

Catalytic enantioselective synthesis of fluoromethylated stereocenters by asymmetric hydrogenation
por: Yang, Jianping, et al.
Publicado: (2022)

Asymmetric Construction of All-Carbon Quaternary Stereocenters by Chiral-Auxiliary-Mediated Claisen Rearrangement and Total Synthesis of (+)-Bakuchiol
por: Takao, Ken-ichi, et al.
Publicado: (2012)

Cross-dehydrogenative coupling enables enantioselective access to CF(3)-substituted all-carbon quaternary stereocenters
por: Pan, Xiaoguang, et al.
Publicado: (2020)

Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters
por: Patel, Kaushalendra, et al.
Publicado: (2022)

Biocatalytic Conversion of Cyclic Ketones Bearing α‐Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium‐Sized Carbocycles
por: Morrill, Charlotte, et al.
Publicado: (2018)

Enantioselective [2 + 2] cycloaddition of N-allenamides with cyclic N-sulfonylketimines: access to polysubstituted azetidines bearing quaternary stereocenters
por: Liu, Ren-Rong, et al.
Publicado: (2017)

Highly Enantioselective Iridium(I)‐Catalyzed Hydrocarbonation of Alkenes: A Versatile Approach to Heterocyclic Systems Bearing Quaternary Stereocenters
por: Arribas, Andrés, et al.
Publicado: (2021)

Construction of polycyclic structures with vicinal all-carbon quaternary stereocenters via an enantioselective photoenolization/Diels–Alder reaction
por: Hou, Min, et al.
Publicado: (2021)

Organocatalytic enantioselective S(N)1-type dehydrative nucleophilic substitution: access to bis(indolyl)methanes bearing quaternary carbon stereocenters
por: Zhu, Wen-Run, et al.
Publicado: (2021)

Nickel-catalyzed enantioselective α-heteroarylation of ketones via C–F bond activation to construct all-carbon quaternary stereocenters
por: Gu, Xiaodong, et al.
Publicado: (2022)

Synthesis of cis-hydrindan-2,4-diones bearing an all-carbon quaternary center by a Danheiser annulation
por: Saborit, Gisela V, et al.
Publicado: (2018)

Asymmetric construction of acyclic quaternary stereocenters via direct enantioselective additions of α-alkynyl ketones to allenamides
por: Wang, Jiawen, et al.
Publicado: (2021)

Asymmetric Synthesis of Spirocyclopentane Oxindoles Containing Four Consecutive Stereocenters and Quaternary α-Nitro Esters via Organocatalytic Enantioselective Michael–Michael Cascade Reactions
por: Chaudhari, Prakash D., et al.
Publicado: (2019)

Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Lactams: Enantioselective Construction of All-Carbon Quaternary Stereocenters in Saturated Nitrogen-Containing Heterocycles
por: Zhang, Tianyi, et al.
Publicado: (2023)

Organocatalytic asymmetric formal oxidative coupling for the construction of all-aryl quaternary stereocenters
por: Li, Zhiyang, et al.
Publicado: (2021)

Enantioselective [3+2]-cycloaddition of 2,3-disubstituted cyclobutenones: vicinal quaternary stereocenters construction and skeletal functionalization
por: Lu, Licheng, et al.
Publicado: (2023)

Stereocontrolled access to δ-lactone-fused-γ-lactams bearing angular benzylic quaternary stereocenters
por: Beng, Timothy K., et al.
Publicado: (2022)

Enantioselective Synthesis of α-Quaternary Mannich Adducts by Palladium-Catalyzed Allylic Alkylation: Total Synthesis of (+)-Sibirinine
por: Numajiri, Yoshitaka, et al.
Publicado: (2015)

Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters
por: Fairchild, Molly E., et al.
Publicado: (2022)

Regiodivergent synthesis of sulfone-tethered lactam–lactones bearing four contiguous stereocenters
por: Beng, Timothy K., et al.
Publicado: (2023)

Enantioselective synthesis of Iboga alkaloids and vinblastine via rearrangements of quaternary ammoniums
por: Zhang, Yun, et al.
Publicado: (2016)

Stereospecific Cross Couplings To Set Benzylic, All-Carbon Quaternary Stereocenters in High Enantiopurity
por: Zhou, Qi, et al.
Publicado: (2016)

Doubly stereoconvergent construction of vicinal all-carbon quaternary and tertiary stereocenters by Cu/Mg-catalyzed propargylic substitution
por: Pu, Xiang, et al.
Publicado: (2022)

Enantioselective Construction of Tertiary Fluoride Stereocenters by Organocatalytic Fluorocyclization
por: Wang, Qiang, et al.
Publicado: (2020)

The enantioselective total synthesis of laurendecumallene B
por: Taylor, Cooper A., et al.
Publicado: (2020)

Quaternary Stereocenters via an Enantioconvergent Catalytic S(N)1 Reaction
por: Wendlandt, Alison E., et al.
Publicado: (2018)

Construction of 4-hydroxycoumarin derivatives with adjacent quaternary and tertiary stereocenters via ternary catalysis
por: Zhang, Mengchu, et al.
Publicado: (2023)

Organocatalytic sulfa-Michael/aldol cascade: constructing functionalized 2,5-dihydrothiophenes bearing a quaternary carbon stereocenter
por: Zhu, Xiao-Yu, et al.
Publicado: (2018)

Isoindolinones as Michael Donors under Phase Transfer Catalysis: Enantioselective Synthesis of Phthalimidines Containing a Tetrasubstituted Carbon Stereocenter
por: Scorzelli, Francesco, et al.
Publicado: (2015)

Catalytic Asymmetric Synthesis of Tröger’s Base Analogues with Nitrogen Stereocenter
por: Ma, Chun, et al.
Publicado: (2023)

Enantioselective synthesis of quaternary 3,4-dihydroisoquinolinones via Heck carbonylation reactions: development and application to the synthesis of Minalrestat analogues
por: Cheng, Cang, et al.
Publicado: (2019)

Enantioselective Total Synthesis of (+)-Heilonine
por: Cassaidy, Kyle J., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_rv030gdmn488d5oao3148t5bno