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Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide

BACKGROUND: Tumor-associated macrophages (TAMs) are the major component of tumor-infiltrating immune cells. Macrophages are broadly categorized as M1 or M2 types, and TAMs have been shown to express an M2-like phenotype. TAMs promote tumor progression and contribute to resistance to chemotherapies....

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Detalles Bibliográficos
Autores principales: Lee, Chanju, Jeong, Hyunju, Bae, Younghyeon, Shin, Kyungmoon, Kang, Sinwoo, Kim, Hwikyung, Oh, Jayoung, Bae, Hyunsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555931/
https://www.ncbi.nlm.nih.gov/pubmed/31174610
http://dx.doi.org/10.1186/s40425-019-0610-4