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Targeting of M2-like tumor-associated macrophages with a melittin-based pro-apoptotic peptide
BACKGROUND: Tumor-associated macrophages (TAMs) are the major component of tumor-infiltrating immune cells. Macrophages are broadly categorized as M1 or M2 types, and TAMs have been shown to express an M2-like phenotype. TAMs promote tumor progression and contribute to resistance to chemotherapies....
Autores principales: | Lee, Chanju, Jeong, Hyunju, Bae, Younghyeon, Shin, Kyungmoon, Kang, Sinwoo, Kim, Hwikyung, Oh, Jayoung, Bae, Hyunsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555931/ https://www.ncbi.nlm.nih.gov/pubmed/31174610 http://dx.doi.org/10.1186/s40425-019-0610-4 |
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