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Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations
BACKGROUND: Neutrophils and eosinophils are multifunctional granulocytes derived from common myelocytic-committed progenitor cells. Severe congenital neutropenia 1 (SCN1) caused by ELANE mutations is a rare disease characterized by very low numbers of circulating neutrophils. Little is known about t...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555947/ https://www.ncbi.nlm.nih.gov/pubmed/31176364 http://dx.doi.org/10.1186/s12887-019-1556-x |