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Functional characteristics of circulating granulocytes in severe congenital neutropenia caused by ELANE mutations

BACKGROUND: Neutrophils and eosinophils are multifunctional granulocytes derived from common myelocytic-committed progenitor cells. Severe congenital neutropenia 1 (SCN1) caused by ELANE mutations is a rare disease characterized by very low numbers of circulating neutrophils. Little is known about t...

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Detalles Bibliográficos
Autores principales:	Liu, Qiao, Sundqvist, Martina, Li, Wenyan, Holdfeldt, André, Zhang, Liang, Björkman, Lena, Bylund, Johan, Dahlgren, Claes, Wang, Cai, Zhao, Xiaodong, Forsman, Huamei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555947/ https://www.ncbi.nlm.nih.gov/pubmed/31176364 http://dx.doi.org/10.1186/s12887-019-1556-x

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