Codon usage optimization in pluripotent embryonic stem cells

BACKGROUND: The uneven use of synonymous codons in the transcriptome regulates the efficiency and fidelity of protein translation rates. Yet, the importance of this codon bias in regulating cell state-specific expression programmes is currently debated. Here, we ask whether different codon usage con...

Descripción completa

Detalles Bibliográficos
Autores principales: Bornelöv, Susanne, Selmi, Tommaso, Flad, Sophia, Dietmann, Sabine, Frye, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555954/
https://www.ncbi.nlm.nih.gov/pubmed/31174582
http://dx.doi.org/10.1186/s13059-019-1726-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555954/
https://www.ncbi.nlm.nih.gov/pubmed/31174582
http://dx.doi.org/10.1186/s13059-019-1726-z

Ejemplares similares