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Chronic obstructive pulmonary disease upper airway microbiota alpha diversity is associated with exacerbation phenotype: a case-control observational study
BACKGROUND: Chronic obstructive pulmonary disease (COPD) frequent exacerbators (FE) suffer increased morbidity and mortality compared to infrequent exacerbators (IE). The association between the oral and sputum microbiota and exacerbation phenotype is not well defined. The objective of this study wa...
Autores principales: | Pragman, Alexa A., Knutson, Katherine A., Gould, Trevor J., Isaacson, Richard E., Reilly, Cavan S., Wendt, Chris H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555967/ https://www.ncbi.nlm.nih.gov/pubmed/31174538 http://dx.doi.org/10.1186/s12931-019-1080-4 |
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