Resistance and resilience to Alzheimer’s disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort

Alzheimer’s disease neuropathologic change (ADNC) is defined by progressive accumulation of β-amyloid plaques and hyperphosphorylated tau (pTau) neurofibrillary tangles across diverse regions of brain. Non-demented individuals who reach advanced age without significant ADNC are considered to be resi...

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Detalles Bibliográficos
Autores principales: Latimer, Caitlin S., Burke, Bridget T., Liachko, Nicole F., Currey, Heather N., Kilgore, Mitchell D., Gibbons, Laura E., Henriksen, Jonathan, Darvas, Martin, Domoto-Reilly, Kimiko, Jayadev, Suman, Grabowski, Tom J., Crane, Paul K., Larson, Eric B., Kraemer, Brian C., Bird, Thomas D., Keene, C. Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556006/
https://www.ncbi.nlm.nih.gov/pubmed/31174609
http://dx.doi.org/10.1186/s40478-019-0743-1

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