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Extracellular lipid loading augments hypoxic paracrine signaling and promotes glioma angiogenesis and macrophage infiltration

BACKGROUND: Primary brain tumors, in particular glioblastoma (GBM), remain among the most challenging cancers. Like most malignant tumors, GBM is characterized by hypoxic stress that triggers paracrine, adaptive responses, such as angiogenesis and macrophage recruitment, rescuing cancer cells from m...

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Detalles Bibliográficos
Autores principales:	Offer, Svenja, Menard, Julien A., Pérez, Julio Enríquez, de Oliveira, Kelin G., Chandran, Vineesh Indira, Johansson, Maria C., Bång-Rudenstam, Anna, Siesjö, Peter, Ebbesson, Anna, Hedenfalk, Ingrid, Sundgren, Pia C., Darabi, Anna, Belting, Mattias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556032/ https://www.ncbi.nlm.nih.gov/pubmed/31174567 http://dx.doi.org/10.1186/s13046-019-1228-6

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