Houttuynia cordata Thunb. and its bioactive compound 2-undecanone significantly suppress benzo(a)pyrene-induced lung tumorigenesis by activating the Nrf2-HO-1/NQO-1 signaling pathway

BACKGROUND: Lung cancer remains the most common cause of cancer-related deaths, with a high incidence and mortality in both sexes worldwide. Chemoprevention has been the most effective strategy for lung cancer prevention. Thus, exploring novel and effective candidate agents with low toxicity for che...

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Detalles Bibliográficos
Autores principales: Lou, Yanmei, Guo, Zhenzhen, Zhu, Yuanfeng, Kong, Muyan, Zhang, Rongrong, Lu, Linlin, Wu, Feichi, Liu, Zhongqiu, Wu, Jinjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556055/
https://www.ncbi.nlm.nih.gov/pubmed/31174565
http://dx.doi.org/10.1186/s13046-019-1255-3

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