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Bone Vascular Niche E-selectin Induces Mesenchymal-Epithelial Transition and Wnt Activation in Cancer Cells to Promote Bone Metastasis

How disseminated tumor cells (DTCs) engage specific stromal components in distant organs for survival and outgrowth is a critical but poorly understood step of the metastatic cascade. Previous studies have demonstrated the importance of the epithelial-mesenchymal transition (EMT) in promoting the ca...

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Detalles Bibliográficos
Autores principales: Esposito, Mark, Mondal, Nandini, Greco, Todd M., Wei, Yong, Spadazzi, Chiara, Lin, Song-Chang, Zheng, Hanqiu, Cheung, Corey, Magnani, John L, Lin, Sue-Hwa, Cristea, Ileana M., Sackstein, Robert, Kang, Yibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556210/
https://www.ncbi.nlm.nih.gov/pubmed/30988423
http://dx.doi.org/10.1038/s41556-019-0309-2