Mitochondrial Entry of Cytotoxic Proteases: A New Insight into the Granzyme B Cell Death Pathway

The mitochondria represent an integration and amplification hub for various death pathways including that mediated by granzyme B (GB), a granule enzyme expressed by cytotoxic lymphocytes. GB activates the proapoptotic B cell CLL/lymphoma 2 (Bcl-2) family member BH3-interacting domain death agonist (...

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Detalles Bibliográficos
Autor principal: Martinvalet, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556269/
https://www.ncbi.nlm.nih.gov/pubmed/31249651
http://dx.doi.org/10.1155/2019/9165214

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556269/
https://www.ncbi.nlm.nih.gov/pubmed/31249651
http://dx.doi.org/10.1155/2019/9165214

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