Cargando…

MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling

Cardiovascular diseases (CVDs) are a major cause of death worldwide. Due to the prevalence of many side effects and incomplete recovery from pharmacotherapies, stem cell therapy is being targeted for the treatment of CVDs. Among the different types of stem cells, endothelial progenitor cells (EPCs)...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lamichane, Shreekrishna, Baek, Sang Hong, Kim, Yeon-Ju, Park, Ji Hye, Dahal Lamichane, Babita, Jang, Woong Bi, Ji, SeungTaek, Lee, Na Kyung, Dehua, Li, Kim, Da Yeon, Kang, Songhwa, Seong, Ha Jong, Yun, Jisoo, Lee, Dong Hyung, Moon, Hyung Ryong, Chung, Hae Young, Kwon, Sang-Mo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556284/ https://www.ncbi.nlm.nih.gov/pubmed/31223423 http://dx.doi.org/10.1155/2019/6492029

Ejemplares similares

Cytoprotective Roles of a Novel Compound, MHY-1684, against Hyperglycemia-Induced Oxidative Stress and Mitochondrial Dysfunction in Human Cardiac Progenitor Cells
por: Jang, Woong Bi, et al.
Publicado: (2018)

Pivotal Roles of Peroxisome Proliferator-Activated Receptors (PPARs) and Their Signal Cascade for Cellular and Whole-Body Energy Homeostasis
por: Lamichane, Shreekrishna, et al.
Publicado: (2018)

Hypoxia-dependent mitochondrial fission regulates endothelial progenitor cell migration, invasion, and tube formation
por: Kim, Da Yeon, et al.
Publicado: (2018)

A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells
por: Tae, In Hwan, et al.
Publicado: (2020)

Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair
por: Park, Ji Hye, et al.
Publicado: (2021)

Author Correction: Human cardiac stem cells rejuvenated by modulating autophagy with MHY-1685 enhance the therapeutic potential for cardiac repair
por: Park, Ji Hye, et al.
Publicado: (2022)

Pharmacological inhibition of mTOR attenuates replicative cell senescence and improves cellular function via regulating the STAT3-PIM1 axis in human cardiac progenitor cells
por: Park, Ji Hye, et al.
Publicado: (2020)

Author Correction: Pharmacological inhibition of mTOR attenuates replicative cell senescence and improves cellular function via regulating the STAT3-PIM1 axis in human cardiac progenitor cells
por: Park, Ji Hye, et al.
Publicado: (2023)

Long-Term Priming by Three Small Molecules Is a Promising Strategy for Enhancing Late Endothelial Progenitor Cell Bioactivities
por: Kim, Yeon-Ju, et al.
Publicado: (2018)

A New Synthetic Histone Deacetylase Inhibitor, MHY2256, Induces Apoptosis and Autophagy Cell Death in Endometrial Cancer Cells via p53 Acetylation
por: De, Umasankar, et al.
Publicado: (2018)

A New Histone Deacetylase Inhibitor, MHY4381, Induces Apoptosis via Generation of Reactive Oxygen Species in Human Prostate Cancer Cells
por: Richa, Sachan, et al.
Publicado: (2020)

Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion
por: Choi, Yeon Ja, et al.
Publicado: (2012)

Correction: Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion
por: Choi, Yeon Ja, et al.
Publicado: (2013)

Anti-Inflammatory Effects of the Novel Barbiturate Derivative MHY2699 in an MPTP-Induced Mouse Model of Parkinson’s Disease
por: Lee, Seulah, et al.
Publicado: (2021)

MHY2251, a New SIRT1 Inhibitor, Induces Apoptosis via JNK/p53 Pathway in HCT116 Human Colorectal Cancer Cells
por: Kang, Yong Jung, et al.
Publicado: (2023)

Anticancer Effects of a New SIRT Inhibitor, MHY2256, against Human Breast Cancer MCF-7 Cells via Regulation of MDM2-p53 Binding
por: Park, Eun Young, et al.
Publicado: (2016)

A New Histone Deacetylase Inhibitor, MHY219, Inhibits the Migration of Human Prostate Cancer Cells via HDAC1
por: De, Umasankar, et al.
Publicado: (2015)

Angiotensin II Attenuates the Bioactivities of Human Endothelial Progenitor Cells via Downregulation of β2-Adrenergic Receptor
por: Lee, Seon Jin, et al.
Publicado: (2018)

Thiobarbiturate-Derived Compound MHY1025 Alleviates Renal Fibrosis by Modulating Oxidative Stress, Epithelial Inflammation, and Fibroblast Activation
por: Kim, Jeongwon, et al.
Publicado: (2023)

Novel SIRT Inhibitor, MHY2256, Induces Cell Cycle Arrest, Apoptosis, and Autophagic Cell Death in HCT116 Human Colorectal Cancer Cells
por: Kim, Min Jeong, et al.
Publicado: (2020)

Pro-apoptotic effect of the novel benzylidene derivative MHY695 in human colon cancer cells
por: Heo, Gwangbeom, et al.
Publicado: (2019)

Adequate concentration of B cell leukemia/lymphoma 3 (Bcl3) is required for pluripotency and self-renewal of mouse embryonic stem cells via downregulation of Nanog transcription
por: Kang, Songhwa, et al.
Publicado: (2018)

PPARα Agonist, MHY3200, Alleviates Renal Inflammation during Aging via Regulating ROS/Akt/FoxO1 Signaling
por: Kim, Min Jo, et al.
Publicado: (2021)

High Glucose Causes Human Cardiac Progenitor Cell Dysfunction by Promoting Mitochondrial Fission: Role of a GLUT1 Blocker
por: Choi, He Yun, et al.
Publicado: (2016)

Hepatoprotective Effects of MHY3200 on High-Fat, Diet-Induced, Non-Alcoholic Fatty Liver Disease in Rats
por: Kim, Min Jo, et al.
Publicado: (2018)

Novel PPARα agonist MHY553 alleviates hepatic steatosis by increasing fatty acid oxidation and decreasing inflammation during aging
por: Kim, Seong Min, et al.
Publicado: (2017)

Potent Anti-Diabetic Effects of MHY908, a Newly Synthesized PPAR α/γ Dual Agonist in db/db Mice
por: Park, Min Hi, et al.
Publicado: (2013)

Evaluation of the Novel Synthetic Tyrosinase Inhibitor (Z)-3-(3-bromo-4-hydroxybenzylidene)thiochroman-4-one (MHY1498) In Vitro and In Silico
por: Bang, EunJin, et al.
Publicado: (2018)

MHY1485 enhances X-irradiation-induced apoptosis and senescence in tumor cells
por: Sun, Lue, et al.
Publicado: (2021)

CHIR99021 Augmented the Function of Late Endothelial Progenitor Cells by Preventing Replicative Senescence
por: Rethineswaran, Vinoth Kumar, et al.
Publicado: (2021)

PPAR Pan Agonist MHY2013 Alleviates Renal Fibrosis in a Mouse Model by Reducing Fibroblast Activation and Epithelial Inflammation
por: Son, Minjung, et al.
Publicado: (2023)

MHY2245, a Sirtuin Inhibitor, Induces Cell Cycle Arrest and Apoptosis in HCT116 Human Colorectal Cancer Cells
por: Kang, Yong Jung, et al.
Publicado: (2022)

Impalement injury of the perineum with an iron rod with a minimal injury: A near miss: A case report
por: Shrestha, Bibek Man, et al.
Publicado: (2021)

The Novel PPAR α/γ Dual Agonist MHY 966 Modulates UVB–Induced Skin Inflammation by Inhibiting NF-κB Activity
por: Park, Min Hi, et al.
Publicado: (2013)

Enzyme-Aided Extraction of Fucoidan by AMG Augments the Functionality of EPCs through Regulation of the AKT/Rheb Signaling Pathway
por: Rethineswaran, Vinoth Kumar, et al.
Publicado: (2019)

Notes on linear gate type N2233
por: Smith, B
Publicado: (1967)

Correction: Rethineswaran et al. CHIR99021 Augmented the Function of Late Endothelial Progenitor Cells by Preventing Replicative Senescence. Int. J. Mol. Sci. 2021, 22, 4796
por: Rethineswaran, Vinoth Kumar, et al.
Publicado: (2022)

MHY4571, a novel diarylcyclohexanone derivative, exerts anti-cancer activity by regulating the PKA-cAMP-response element-binding protein pathway in squamous cell lung cancer
por: Chung, Jae Heun, et al.
Publicado: (2022)

Selected Risk Factors and Pattern of Semen Abnormality in Male Partners of Infertile Couples in Eastern Nepal: A Descriptive Cross-sectional Study
por: Pokhrel, Sita, et al.
Publicado: (2020)

SIRT1 ubiquitination is regulated by opposing activities of APC/C-Cdh1 and AROS during stress-induced premature senescence
por: Lee, Sang Hyup, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_sk8lrkv1inelp6chb3udre32hu