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Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K(+)-Cl(−) Cotransporter KCC2

Chloride (Cl(−)) homeostasis is an essential process involved in neuronal signalling and cell survival. Inadequate regulation of intracellular Cl(−) interferes with synaptic signalling and is implicated in several neurological diseases. The main inhibitory neurotransmitter of the central nervous sys...

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Detalles Bibliográficos
Autores principales: Tillman, Luke, Zhang, Jinwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556333/
https://www.ncbi.nlm.nih.gov/pubmed/31240228
http://dx.doi.org/10.1155/2019/8941046