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Crossing the Chloride Channel: The Current and Potential Therapeutic Value of the Neuronal K(+)-Cl(−) Cotransporter KCC2
Chloride (Cl(−)) homeostasis is an essential process involved in neuronal signalling and cell survival. Inadequate regulation of intracellular Cl(−) interferes with synaptic signalling and is implicated in several neurological diseases. The main inhibitory neurotransmitter of the central nervous sys...
Autores principales: | Tillman, Luke, Zhang, Jinwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556333/ https://www.ncbi.nlm.nih.gov/pubmed/31240228 http://dx.doi.org/10.1155/2019/8941046 |
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