Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient

Sugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m(2)) developed asystole, following coadministration with dexmedetomidine,...

Descripción completa

Detalles Bibliográficos
Autores principales: Gajewski, Michal, Esochaghi, Sorochi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556339/
https://www.ncbi.nlm.nih.gov/pubmed/31263603
http://dx.doi.org/10.1155/2019/2709568
_version_ 1783425315392978944
author Gajewski, Michal
Esochaghi, Sorochi
author_facet Gajewski, Michal
Esochaghi, Sorochi
author_sort Gajewski, Michal
collection PubMed
description Sugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m(2)) developed asystole, following coadministration with dexmedetomidine, for rapid reversal after deep blockade. Although 16mg/kg of actual body weight is recommended for prompt reversal of deep blockade, dosing adjustments may be prudent in the obese population, especially when used in conjunction with other negative chronotropic agents.
format Online
Article
Text
id pubmed-6556339
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-65563392019-07-01 Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient Gajewski, Michal Esochaghi, Sorochi Case Rep Anesthesiol Case Report Sugammadex is increasingly used to reverse aminosteroid neuromuscular blocking agents. Dosing is calculated based on actual body weight, even for those who are obese. We report a case where a super obese patient (BMI 58.5 kg/m(2)) developed asystole, following coadministration with dexmedetomidine, for rapid reversal after deep blockade. Although 16mg/kg of actual body weight is recommended for prompt reversal of deep blockade, dosing adjustments may be prudent in the obese population, especially when used in conjunction with other negative chronotropic agents. Hindawi 2019-05-21 /pmc/articles/PMC6556339/ /pubmed/31263603 http://dx.doi.org/10.1155/2019/2709568 Text en Copyright © 2019 Michal Gajewski and Sorochi Esochaghi. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Gajewski, Michal
Esochaghi, Sorochi
Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title_full Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title_fullStr Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title_full_unstemmed Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title_short Transient Asystole after Sugammadex Administration for Immediate Reversal of Deep Blockade while on Dexmedetomidine Infusion in a Super Obese Patient
title_sort transient asystole after sugammadex administration for immediate reversal of deep blockade while on dexmedetomidine infusion in a super obese patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556339/
https://www.ncbi.nlm.nih.gov/pubmed/31263603
http://dx.doi.org/10.1155/2019/2709568
work_keys_str_mv AT gajewskimichal transientasystoleaftersugammadexadministrationforimmediatereversalofdeepblockadewhileondexmedetomidineinfusioninasuperobesepatient
AT esochaghisorochi transientasystoleaftersugammadexadministrationforimmediatereversalofdeepblockadewhileondexmedetomidineinfusioninasuperobesepatient

Ejemplares similares