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Tracing the effect of the melanocortin-4 receptor pathway in obesity: study design and methodology of the TEMPO registry
Purpose: The hypothalamic melanocortin-4 receptor (MC4R) pathway, a component of the central melanocortin pathway, regulates energy balance and satiety. Rare genetic disorders of obesity may be characterized by impaired MC4R pathway signaling, which results in early-onset severe obesity and insatiab...
Autores principales: | Eneli, Ihuoma, Xu, Jinyu, Webster, Matthew, McCagg, Amy, Van Der Ploeg, Lex, Garfield, Alastair S, Estrada, Elizabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556479/ https://www.ncbi.nlm.nih.gov/pubmed/31239751 http://dx.doi.org/10.2147/TACG.S199092 |
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