Sodium sulfide selectively induces oxidative stress, DNA damage, and mitochondrial dysfunction and radiosensitizes glioblastoma (GBM) cells.

Glioblastoma (GBM) has a poor prognosis despite intensive treatment with surgery and chemoradiotherapy. Previous studies using dose-escalated radiotherapy have demonstrated improved survival; however, increased rates of radionecrosis have limited its use. Development of radiosensitizers could improv...

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Detalles Bibliográficos
Autores principales: Xiao, Adam Y., Maynard, Matthew R., Piett, Cortt G., Nagel, Zachary D., Alexander, J. Steven, Kevil, Christopher G., Berridge, Michael V., Pattillo, Christopher B., Rosen, Lane R., Miriyala, Sumitra, Harrison, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556549/
https://www.ncbi.nlm.nih.gov/pubmed/31176262
http://dx.doi.org/10.1016/j.redox.2019.101220

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